Human FEZ1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FEZ1
Locus ID	9638
Kit Components	GA106456G1, FEZ1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106456G2, FEZ1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106456G3, FEZ1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005103, NM_022549
Synonyms	fasciculation and elongation protein zeta 1 (zygin I); zygin 1
Summary	This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]

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