Human CDC42 Binding Protein Kinase Beta (CDC42BPB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDC42BPB
Locus ID	9578
Kit Components	GA106413G1, CDC42 Binding Protein Kinase Beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106413G2, CDC42 Binding Protein Kinase Beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106413G3, CDC42 Binding Protein Kinase Beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_006035
Synonyms	MRCKB
Summary	This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008]

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