Human NR1D1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NR1D1
Locus ID	9572
Kit Components	GA106408G1, NR1D1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106408G2, NR1D1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106408G3, NR1D1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021724
Synonyms	ear-1; EAR1; hRev; THRA1; THRAL
Summary	This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013]

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