Human POLR1C activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	POLR1C
Locus ID	9533
Kit Components	GA106378G1, POLR1C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106378G2, POLR1C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106378G3, POLR1C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_004875, NM_203290, NM_001318876, NM_001363658
Synonyms	RP3-337H4.4; RPA5; RPA39; RPA40; RPAC1; TCS3
Summary	The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

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