Human TMEM59 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TMEM59
Locus ID	9528
Kit Components	GA106373G1, TMEM59 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106373G2, TMEM59 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106373G3, TMEM59 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001305043, NM_001305049, NM_001305050, NM_001305051, NM_001305052, NM_001305066, NM_004872
Synonyms	C1orf8; DCF1; HSPC001; PRO195; UNQ169
Summary	This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

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