Human ARHGEF6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGEF6
Locus ID	9459
Kit Components	GA106318G1, ARHGEF6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106318G2, ARHGEF6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106318G3, ARHGEF6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001306177, NM_004840
Synonyms	alpha-PIX; alphaPIX; Cool-2; COOL2; MRX46; PIXA
Summary	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008]

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