Human CD101 activation kit by CRISPRa

CAT#: GA106270

CD101 CRISPRa kit - CRISPR gene activation of human CD101 molecule



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
CD101 rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


CD101 (Myc-DDK-tagged)-Human CD101 molecule (CD101)
    • 10 ug

CNY 10,664.00


CD101 rabbit polyclonal antibody
    • 25 ul

CNY 800.00
CNY 1,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CD101
Locus ID 9398
Kit Components

GA106270G1, CD101 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106270G2, CD101 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106270G3, CD101 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001256106, NM_001256109, NM_001256111, NM_004258
Synonyms EWI-101; IGSF2; V7
Summary Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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