Human GTF3C4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GTF3C4
Locus ID	9329
Kit Components	GA106218G1, GTF3C4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106218G2, GTF3C4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106218G3, GTF3C4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_012204, NR_133925
Synonyms	KAT12; TF3C-delta; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA
Summary	Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.[UniProtKB/Swiss-Prot Function]

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