Human TRIP12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRIP12
Locus ID	9320
Kit Components	GA106211G1, TRIP12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106211G2, TRIP12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106211G3, TRIP12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001284214, NM_001284215, NM_001284216, NM_004238, NM_001348315, NM_001348316, NM_001348317, NM_001348318, NM_001348319, NM_001348320, NM_001348321, NM_001348322, NM_001348323, NM_001348324, NM_001348325, NM_001348326, NM_001348327, NM_001348328, NM_001348329, NM_001348330, NM_001348331, NM_001348332, NM_001348333, NM_001348334, NM_001348335, NM_001348336
Synonyms	TRIP-12; ULF
Summary	The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017]

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