Human ATP6V1F activation kit by CRISPRa

CAT#: GA106199

ATP6V1F CRISPRa kit - CRISPR gene activation of human ATPase H+ transporting V1 subunit F



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
ATP6V1F mouse monoclonal antibody, clone OTI1B8 (formerly 1B8)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


ATP6V1F (Myc-DDK-tagged)-Human ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F (ATP6V1F), transcript variant 1
    • 10 ug

CNY 1,200.00
CNY 3,705.00


ATP6V1F mouse monoclonal antibody, clone OTI5F10 (formerly 5F10)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol ATP6V1F
Locus ID 9296
Kit Components

GA106199G1, ATP6V1F gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106199G2, ATP6V1F gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106199G3, ATP6V1F gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001198909, NM_004231
Synonyms ATP6S14; VATF; Vma7
Summary This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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