Human GEF H1 (ARHGEF2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGEF2
Locus ID	9181
Kit Components	GA106120G1, GEF H1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106120G2, GEF H1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106120G3, GEF H1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001162383, NM_001162384, NM_004723, NM_001350110, NM_001350111, NM_001350112
Synonyms	GEF; GEF-H1; GEFH1; LFP40; P40
Summary	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]

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