GEF H1 (ARHGEF2) Mouse Monoclonal Antibody [Clone ID: OTI5F2]

Specifications

Product Data
Clone Name	OTI5F2
Applications	FC, WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ARHGEF2 (NP_004714) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	108.1 kDa
Gene Name	Rho/Rac guanine nucleotide exchange factor 2
Database Link	NP_004714 Entrez Gene 16800 MouseEntrez Gene 310635 RatEntrez Gene 9181 Human UniProt ID Q92974
Background	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2009]
Synonyms	GEF; GEF-H1; GEFH1; LFP40; P40
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Pathogenic Escherichia coli infection

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