Human Exonuclease 1 (EXO1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EXO1
Locus ID	9156
Kit Components	GA106105G1, Exonuclease 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106105G2, Exonuclease 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106105G3, Exonuclease 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001319224, NM_003686, NM_006027, NM_130398
Synonyms	HEX1; hExoI
Summary	This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008]

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