Human P2X6 (P2RX6) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	P2RX6
Locus ID	9127
Kit Components	GA106080G1, P2X6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106080G2, P2X6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106080G3, P2X6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001159554, NM_005446, NM_001349874, NM_001349875, NM_001349876
Synonyms	P2RXL1; P2X6; P2XM
Summary	The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]

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