Human Synaptotagmin VII (SYT7) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SYT7
Locus ID	9066
Kit Components	GA106030G1, Synaptotagmin VII gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106030G2, Synaptotagmin VII gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106030G3, Synaptotagmin VII gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001252065, NM_001300773, NM_004200, NM_001370210, NM_001370211, NM_001365809
Synonyms	IPCA-7; IPCA7; PCANAP7; SYT-VII; SYTVII
Summary	This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

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