Human NFkB Inducing Kinase NIK (MAP3K14) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAP3K14
Locus ID	9020
Kit Components	GA105993G1, NFkB Inducing Kinase NIK gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105993G2, NFkB Inducing Kinase NIK gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105993G3, NFkB Inducing Kinase NIK gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_003954
Synonyms	FTDCR1B; HS; HSNIK; NIK
Summary	This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]

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