Human NFkB Inducing Kinase NIK (MAP3K14) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAP3K14
Locus ID	9020
Kit Components	GA105993G1, NFkB Inducing Kinase NIK gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105993G2, NFkB Inducing Kinase NIK gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105993G3, NFkB Inducing Kinase NIK gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003954
Synonyms	FTDCR1B; HS; HSNIK; NIK
Summary	This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]

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