Human MSK2 / RSK-B (RPS6KA4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RPS6KA4
Locus ID	8986
Kit Components	GA105974G1, MSK2 / RSK-B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105974G2, MSK2 / RSK-B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105974G3, MSK2 / RSK-B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001006944, NM_001300802, NM_003942, NM_001318361
Synonyms	MSK2; RSK-B
Summary	This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

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