Human L Kynurenine Hydrolase (KYNU) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KYNU
Locus ID	8942
Kit Components	GA105961G1, L Kynurenine Hydrolase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105961G2, L Kynurenine Hydrolase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105961G3, L Kynurenine Hydrolase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001032998, NM_001199241, NM_003937
Synonyms	KYNUU
Summary	Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

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