Human EIF2B3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EIF2B3
Locus ID	8891
Kit Components	GA105922G1, EIF2B3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105922G2, EIF2B3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105922G3, EIF2B3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166588, NM_001261418, NM_020365
Synonyms	EIF-2B; EIF2Bgamma
Summary	The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

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