Human CCN6 activation kit by CRISPRa

CAT#: GA105880

CCN6 CRISPRa kit - CRISPR gene activation of human cellular communication network factor 6



  See Other Versions

CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
CCN6 rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


WISP3 (Myc-DDK-tagged)-Human WNT1 inducible signaling pathway protein 3 (WISP3), transcript variant 1
    • 10 ug

CNY 3,656.00
CNY 3,990.00


WISP3 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CCN6
Locus ID 8838
Kit Components

GA105880G1, CCN6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105880G2, CCN6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105880G3, CCN6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_003880, NM_130396, NM_198239, NR_125353, NR_125354
Synonyms CCN6; LIBC; PPAC; PPD; WISP-3
Summary This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...