Human TIF1 alpha (TRIM24) activation kit by CRISPRa

CAT#: GA105851

TRIM24 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 24



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
TRIM24 mouse monoclonal antibody, clone OTI2D9 (formerly 2D9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TRIM24 (Myc-DDK-tagged)-Human tripartite motif containing 24 (TRIM24), transcript variant 1
    • 10 ug

CNY 10,968.00


TRIM24 mouse monoclonal antibody, clone OTI1G5 (formerly 1G5)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol TRIM24
Locus ID 8805
Kit Components

GA105851G1, TIF1 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105851G2, TIF1 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105851G3, TIF1 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_003852, NM_015905
Synonyms hTIF1; PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA
Summary The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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