Human MNK1 (MKNK1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MKNK1
Locus ID	8569
Kit Components	GA105680G1, MNK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105680G2, MNK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105680G3, MNK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001135553, NM_003684, NM_198973, NR_024174, NR_024176, NR_146512, NR_024175
Synonyms	MNK1
Summary	This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]

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