Human Tyrosyl tRNA synthetase (YARS) activation kit by CRISPRa
CAT#: GA105676
YARS CRISPRa kit - CRISPR gene activation of human tyrosyl-tRNA synthetase
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | YARS1 |
Locus ID | 8565 |
Kit Components | GA105676G1, Tyrosyl tRNA synthetase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105676G2, Tyrosyl tRNA synthetase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105676G3, Tyrosyl tRNA synthetase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_003680 |
Synonyms | CMTDIC; TYRRS; YRS; YTS |
Summary | Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN404590 | YARS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |