Human CDC14B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDC14B
Locus ID	8555
Kit Components	GA105667G1, CDC14B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105667G2, CDC14B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105667G3, CDC14B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001077181, NM_003671, NM_033331, NM_033332, NM_001351567, NM_001351568, NM_001351569, NM_001351570, NR_147239
Synonyms	Cdc14B1; Cdc14B2; CDC14B3; hCDC14B
Summary	The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

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