Human RAD54 (RAD54L) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RAD54L
Locus ID	8438
Kit Components	GA105572G1, RAD54 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105572G2, RAD54 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105572G3, RAD54 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142548, NM_003579, NM_001370766
Synonyms	hHR54; HR54; hRAD54; RAD54A
Summary	The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]

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