Human AP3B2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AP3B2
Locus ID	8120
Kit Components	GA105417G1, AP3B2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105417G2, AP3B2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105417G3, AP3B2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001278511, NM_001278512, NM_004644, NM_001348440, NM_001348441
Synonyms	NAPTB
Summary	Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy. [provided by RefSeq, Feb 2017]

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