Human Semaphorin 3B (SEMA3B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SEMA3B
Locus ID	7869
Kit Components	GA105343G1, Semaphorin 3B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105343G2, Semaphorin 3B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105343G3, Semaphorin 3B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001005914, NM_001290060, NM_001290061, NM_001290062, NM_001290063, NM_004636, NR_110697
Synonyms	LUCA-1; SemA; SEMA5; SEMAA; semaV
Summary	The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]

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