Human Plzf (ZBTB16) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZBTB16
Locus ID	7704
Kit Components	GA105263G1, Plzf gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105263G2, Plzf gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105263G3, Plzf gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001018011, NM_006006, NM_001354750, NM_001354751, NM_001354752
Synonyms	PLZF; ZNF145
Summary	This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

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