Human Ezrin (EZR) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EZR
Locus ID	7430
Kit Components	GA105121G1, Ezrin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105121G2, Ezrin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105121G3, Ezrin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001111077, NM_003379
Synonyms	CVIL; CVL; HEL-S-105; VIL2
Summary	The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]

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