Human UROD activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UROD
Locus ID	7389
Kit Components	GA105092G1, UROD gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105092G2, UROD gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105092G3, UROD gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000374, NR_036510, NR_158185, NR_158184
Synonyms	PCT; UPD
Summary	This gene encodes an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.[provided by RefSeq, Aug 2010]

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