Human Tropomyosin 2 (TPM2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TPM2
Locus ID	7169
Kit Components	GA104953G1, Tropomyosin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104953G2, Tropomyosin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104953G3, Tropomyosin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001145822, NM_001301226, NM_001301227, NM_003289, NM_213674
Synonyms	AMCD1; arthrogryposis multiplex congenital, distal, type 1; DA1; DA2B; NEM4; OTTHUMP00000021357; TMSB; tropomyosin 2 (beta)
Summary	This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]

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