Human TGF alpha (TGFA) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TGFA
Locus ID	7039
Kit Components	GA104846G1, TGF alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104846G2, TGF alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104846G3, TGF alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001099691, NM_001308158, NM_001308159, NM_003236
Synonyms	TFGA
Summary	This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

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