Human SH3BP2 activation kit by CRISPRa

CAT#: GA104393

SH3BP2 CRISPRa kit - CRISPR gene activation of human SH3 domain binding protein 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit polyclonal Anti-SH3BP2 Antibody
    • 100 ul

CNY 5,250.00


SH3BP2 (Myc-DDK-tagged)-Human SH3-domain binding protein 2 (SH3BP2), transcript variant 2
    • 10 ug

CNY 4,176.00
CNY 4,560.00


SH3BP2 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SH3BP2
Locus ID 6452
Kit Components

GA104393G1, SH3BP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104393G2, SH3BP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104393G3, SH3BP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001122681, NM_001145855, NM_001145856, NM_003023
Synonyms 3BP-2; 3BP2; CRBM; CRPM; RES4-23
Summary The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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