Human alpha Sarcoglycan (SGCA) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SGCA
Locus ID	6442
Kit Components	GA104383G1, alpha Sarcoglycan gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104383G2, alpha Sarcoglycan gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104383G3, alpha Sarcoglycan gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000023, NM_001135697, NR_135553
Synonyms	50-DAG; A2; adhalin; ADL; DAG2; DMDA2; LGMD2D; SCARMD1
Summary	This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

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