Human RRM1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RRM1
Locus ID	6240
Kit Components	GA104230G1, RRM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104230G2, RRM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104230G3, RRM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033, NM_001318064, NM_001318065, NM_001330193
Synonyms	R1; RIR1; RR1
Summary	This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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