Human P70 S6 Kinase beta (RPS6KB2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RPS6KB2
Locus ID	6199
Kit Components	GA104201G1, P70 S6 Kinase beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104201G2, P70 S6 Kinase beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104201G3, P70 S6 Kinase beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001007071, NM_003952
Synonyms	KLS; P70-beta; P70-beta-1; P70-beta-2; p70S6Kb; S6K-beta2; S6K2; SRK; STK14B
Summary	This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015]

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