Human ROR beta (RORB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RORB
Locus ID	6096
Kit Components	GA104131G1, ROR beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104131G2, ROR beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104131G3, ROR beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006914, NM_001365023
Synonyms	bA133M9.1; NR1F2; ROR-BETA; RZR-BETA; RZRB
Summary	The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]

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