Human Ribonuclease A (RNASE1) activation kit by CRISPRa
CAT#: GA104112
RNASE1 CRISPRa kit - CRISPR gene activation of human ribonuclease A family member 1, pancreatic
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | RNASE1 |
Locus ID | 6035 |
Kit Components | GA104112G1, Ribonuclease A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104112G2, Ribonuclease A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104112G3, Ribonuclease A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_002933, NM_198232, NM_198234, NM_198235 |
Synonyms | RAC1; RIB1; RNS1 |
Summary | This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN402755 | RNASE1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |