Human RGS3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RGS3
Locus ID	5998
Kit Components	GA104092G1, RGS3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104092G2, RGS3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104092G3, RGS3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001276260, NM_001276261, NM_001276262, NM_001282922, NM_001282923, NM_001322214, NM_001322215, NM_017790, NM_021106, NM_130795, NM_134427, NM_144488, NM_144489, NR_074077, NR_074078, NM_001351526
Synonyms	C2PA; RGP3
Summary	This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear. [provided by RefSeq, Jan 2013]

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