Human PCPTP1 (PTPRR) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PTPRR
Locus ID	5801
Kit Components	GA103945G1, PCPTP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103945G2, PCPTP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103945G3, PCPTP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001207015, NM_001207016, NM_002849, NM_130846, NR_073474
Synonyms	EC-PTP; PCPTP1; PTP-SL; PTPBR7; PTPRQ
Summary	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]

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