Human Parathyroid Hormone Receptor 1 (PTH1R) activation kit by CRISPRa

CAT#: GA103909

PTH1R CRISPRa kit - CRISPR gene activation of human parathyroid hormone 1 receptor



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
PTH1R rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


PTH1R (Myc-DDK-tagged)-Human parathyroid hormone 1 receptor (PTH1R), transcript variant 1
    • 10 ug

CNY 4,416.00


PTH1R rabbit polyclonal antibody
    • 25 ul

CNY 800.00
CNY 1,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PTH1R
Locus ID 5745
Kit Components

GA103909G1, Parathyroid Hormone Receptor 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103909G2, Parathyroid Hormone Receptor 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103909G3, Parathyroid Hormone Receptor 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000316, NM_001184744
Synonyms PFE; PTHR; PTHR1
Summary The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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