Human PKC beta 1 (PRKCB) activation kit by CRISPRa

CAT#: GA103769

PRKCB CRISPRa kit - CRISPR gene activation of human protein kinase C beta



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
PKC beta 2 Rabbit monoclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


PRKCB (Myc-DDK-tagged)-Human protein kinase C, beta (PRKCB), transcript variant 1
    • 10 ug

CNY 7,368.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PRKCB
Locus ID 5579
Kit Components

GA103769G1, PKC beta 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103769G2, PKC beta 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103769G3, PKC beta 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_002738, NM_212535
Synonyms PKC-beta; PKCB; PRKCB1; PRKCB2
Summary Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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