Human Major Basic Protein (PRG2) activation kit by CRISPRa

CAT#: GA103749

PRG2 CRISPRa kit - CRISPR gene activation of human proteoglycan 2, pro eosinophil major basic protein



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
PRG2 mouse monoclonal antibody,clone OTI10D10
    • 100 ul

CNY 1,999.00
CNY 2,700.00


PRG2 (Myc-DDK-tagged)-Human proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) (PRG2)
    • 10 ug

CNY 2,400.00
CNY 3,705.00


PRG2 mouse monoclonal antibody,clone OTI1C12
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PRG2
Locus ID 5553
Kit Components

GA103749G1, Major Basic Protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103749G2, Major Basic Protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103749G3, Major Basic Protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001243245, NM_001302926, NM_001302927, NM_002728
Synonyms BMPG; MBP; MBP1
Summary The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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