Human PPAR gamma (PPARG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPARG
Locus ID	5468
Kit Components	GA103688G1, PPAR gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103688G2, PPAR gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103688G3, PPAR gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001330615, NM_005037, NM_015869, NM_138711, NM_138712, NM_001354666, NM_001354667, NM_001354668, NM_001354669, NM_001354670
Synonyms	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma
Summary	This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

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