Human DNA Polymerase gamma (POLG) activation kit by CRISPRa

CAT#: GA103651

POLG CRISPRa kit - CRISPR gene activation of human DNA polymerase gamma, catalytic subunit



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal antibody to DNA polymerase gamma (polymerase (DNA directed), gamma)
    • 100 ul

CNY 6,281.00


POLG (Myc-DDK-tagged)-Human polymerase (DNA directed), gamma (POLG), transcript variant 1
    • 10 ug

CNY 8,624.00


POLG rabbit polyclonal antibody
    • 25 ul

CNY 800.00
CNY 1,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol POLG
Locus ID 5428
Kit Components

GA103651G1, DNA Polymerase gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103651G2, DNA Polymerase gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103651G3, DNA Polymerase gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001126131, NM_002693
Synonyms MDP1; MIRAS; MTDPS4A; MTDPS4B; PEO; POLG1; POLGA; SANDO; SCAE
Summary Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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