Human Alpha 2 Antiplasmin (SERPINF2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SERPINF2
Locus ID	5345
Kit Components	GA103604G1, Alpha 2 Antiplasmin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103604G2, Alpha 2 Antiplasmin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103604G3, Alpha 2 Antiplasmin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000934, NM_001165920, NM_001165921
Synonyms	A2AP; AAP; ALPHA-2-PI; API; PLI
Summary	This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

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