Human PI4KA activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PI4KA
Locus ID	5297
Kit Components	GA103562G1, PI4KA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103562G2, PI4KA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103562G3, PI4KA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002650, NM_058004, NM_001362862, NM_001362863
Synonyms	PI4K-ALPHA; pi4K230; PIK4CA
Summary	This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2018]

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