Human PAM activation kit by CRISPRa
CAT#: GA103382
PAM CRISPRa kit - CRISPR gene activation of human peptidylglycine alpha-amidating monooxygenase
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | PAM |
Locus ID | 5066 |
Kit Components | GA103382G1, PAM gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103382G2, PAM gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103382G3, PAM gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_000919, NM_001177306, NM_001319943, NM_138766, NM_138821, NM_138822, NR_033440, NM_001364582, NM_001364584, NM_001364586, NM_001364588, NM_001364589, NM_001364590, NM_001364593, NM_001364583, NM_001364585, NM_001364587, NM_001364591, NM_001364592, NM_001364594, NR_157231 |
Synonyms | PAL; PHM |
Summary | This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
Documents
Resources
基因表达相关资源 |
Other Versions
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KN202074 | PAM - human gene knockout kit via CRISPR, HDR mediated |
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KN202074BN | PAM - human gene knockout kit via CRISPR, HDR mediated |
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KN202074LP | PAM - human gene knockout kit via CRISPR, HDR mediated |
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KN202074RB | PAM - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN402074 | PAM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
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