Human P2RX7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	P2RX7
Locus ID	5027
Kit Components	GA103356G1, P2RX7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103356G2, P2RX7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103356G3, P2RX7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002562, NM_177427, NR_033948, NR_033949, NR_033950, NR_033951, NR_033952, NR_033953, NR_033954, NR_033955, NR_033956
Synonyms	P2X7
Summary	The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]

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