Human Natriuretic Peptide Receptor C (NPR3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NPR3
Locus ID	4883
Kit Components	GA103260G1, Natriuretic Peptide Receptor C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103260G2, Natriuretic Peptide Receptor C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103260G3, Natriuretic Peptide Receptor C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000908, NM_001204375, NM_001204376, NM_001363652, NM_001364460, NM_001364458
Synonyms	ANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPRC
Summary	This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]

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